Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 499.6 BDBM50342777

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50342777 (4-((3-(4-(benzo[d]thiazol-2-yloxy)phenylamino)-6-a...) Show SMILES OC(=O)c1ccc(CN2CC3CC(Nc4ccc(Oc5nc6ccccc6s5)cc4)C2CCC3)cc1 |THB:7:8:12.11:31.32.33| Show InChI InChI=1S/C29H29N3O3S/c33-28(34)21-10-8-19(9-11-21)17-32-18-20-4-3-6-26(32)25(16-20)30-22-12-14-23(15-13-22)35-29-31-24-5-1-2-7-27(24)36-29/h1-2,5,7-15,20,25-26,30H,3-4,6,16-18H2,(H,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University (GNU) Curated by ChEMBL					Assay Description Inhibition of human leukotriene A4 hydrolase				Eur J Med Chem 46: 1593-603 (2011) Article DOI: 10.1016/j.ejmech.2011.02.007 BindingDB Entry DOI: 10.7270/Q2K64JDG
					More data for this Ligand-Target Pair