Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251626
(4-((4-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)piper...)Show SMILES OC(=O)c1ccc(CN2CCC(CC2)Nc2ccc(Oc3ccc(cc3)-c3ncco3)cc2)cc1 Show InChI InChI=1S/C28H27N3O4/c32-28(33)22-3-1-20(2-4-22)19-31-16-13-24(14-17-31)30-23-7-11-26(12-8-23)35-25-9-5-21(6-10-25)27-29-15-18-34-27/h1-12,15,18,24,30H,13-14,16-17,19H2,(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251626
(4-((4-(4-(4-(oxazol-2-yl)phenoxy)phenylamino)piper...)Show SMILES OC(=O)c1ccc(CN2CCC(CC2)Nc2ccc(Oc3ccc(cc3)-c3ncco3)cc2)cc1 Show InChI InChI=1S/C28H27N3O4/c32-28(33)22-3-1-20(2-4-22)19-31-16-13-24(14-17-31)30-23-7-11-26(12-8-23)35-25-9-5-21(6-10-25)27-29-15-18-34-27/h1-12,15,18,24,30H,13-14,16-17,19H2,(H,32,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase in human whole blood |
Bioorg Med Chem Lett 18: 3895-8 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.041
BindingDB Entry DOI: 10.7270/Q2GQ6XK8 |
More data for this
Ligand-Target Pair | |