Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251520
(4-((4-(2-oxo-2-(4-phenoxyphenylamino)ethyl)piperaz...)Show SMILES OC(=O)c1ccc(CN2CCN(CC(=O)Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 Show InChI InChI=1S/C26H27N3O4/c30-25(27-22-10-12-24(13-11-22)33-23-4-2-1-3-5-23)19-29-16-14-28(15-17-29)18-20-6-8-21(9-7-20)26(31)32/h1-13H,14-19H2,(H,27,30)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by whole blood assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Homo sapiens (Human)) | BDBM50251520
(4-((4-(2-oxo-2-(4-phenoxyphenylamino)ethyl)piperaz...)Show SMILES OC(=O)c1ccc(CN2CCN(CC(=O)Nc3ccc(Oc4ccccc4)cc3)CC2)cc1 Show InChI InChI=1S/C26H27N3O4/c30-25(27-22-10-12-24(13-11-22)33-23-4-2-1-3-5-23)19-29-16-14-28(15-17-29)18-20-6-8-21(9-7-20)26(31)32/h1-13H,14-19H2,(H,27,30)(H,31,32) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Berlex Biosciences
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase (unknown origin) by hydrolase assay |
Bioorg Med Chem Lett 18: 3891-4 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.046
BindingDB Entry DOI: 10.7270/Q20P0ZTV |
More data for this
Ligand-Target Pair | |