Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50084777
(4-((7-(quinolin-2-ylmethoxy)naphthalen-2-ylcarbamo...)Show SMILES OC(=O)c1ccc(COC(=O)Nc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1 Show InChI InChI=1S/C29H22N2O5/c32-28(33)22-7-5-19(6-8-22)17-36-29(34)31-24-12-9-20-11-14-26(16-23(20)15-24)35-18-25-13-10-21-3-1-2-4-27(21)30-25/h1-16H,17-18H2,(H,31,34)(H,32,33) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratorios Menarini
Curated by ChEMBL
| Assay Description
In vitro binding affinity towards Cysteinyl leukotriene D4 receptor by using [3H]-LTD4 binding assay in guinea pig lung membranes |
J Med Chem 43: 392-400 (2000)
BindingDB Entry DOI: 10.7270/Q2DJ5DVX |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50084777
(4-((7-(quinolin-2-ylmethoxy)naphthalen-2-ylcarbamo...)Show SMILES OC(=O)c1ccc(COC(=O)Nc2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1 Show InChI InChI=1S/C29H22N2O5/c32-28(33)22-7-5-19(6-8-22)17-36-29(34)31-24-12-9-20-11-14-26(16-23(20)15-24)35-18-25-13-10-21-3-1-2-4-27(21)30-25/h1-16H,17-18H2,(H,31,34)(H,32,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |