Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 376.4 BDBM50323888

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50323888 (3-(3-(4-(cyclohexa-1,5-dienylmethoxy)phenyl)acrylo...) Show SMILES OC(=O)c1ccc(O)c(c1)C(=O)\C=C\c1ccc(OCC2=CCCC=C2)cc1 |c:25,t:21| Show InChI InChI=1S/C23H20O5/c24-21(20-14-18(23(26)27)9-13-22(20)25)12-8-16-6-10-19(11-7-16)28-15-17-4-2-1-3-5-17/h2,4-14,25H,1,3,15H2,(H,26,27)/b12-8+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
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