Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 471.5 BDBM50323904

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50323904 ((E)-4-(Cyanomethoxy)-3-(3-(4-(4-phenoxybutoxy)phen...) Show SMILES OC(=O)c1ccc(OCC#N)c(c1)C(=O)\C=C\c1ccc(OCCCCOc2ccccc2)cc1 Show InChI InChI=1S/C28H25NO6/c29-16-19-35-27-15-11-22(28(31)32)20-25(27)26(30)14-10-21-8-12-24(13-9-21)34-18-5-4-17-33-23-6-2-1-3-7-23/h1-3,6-15,20H,4-5,17-19H2,(H,31,32)/b14-10+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair