Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Putative hydrolase
(Pseudomonas aeruginosa (strain UCBPP-PA14)) | BDBM50060966
(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)Show InChI InChI=1S/C13H10O3/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9H,(H,14,15) | PDB
UniProtKB/TrEMBL
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| US Patent
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
| Assay Description The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f... |
Bioorg Med Chem Lett 19: 4280-3 (2009)
BindingDB Entry DOI: 10.7270/Q2KW5JC9 |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Klebsiella pneumoniae) | BDBM50060966
(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)Show InChI InChI=1S/C13H10O3/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9H,(H,14,15) | PDB
UniProtKB/TrEMBL
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT The Arctic University of Norway
Curated by ChEMBL
| Assay Description Inhibition of native signal containing Klebsiella pneumoniae OXA-48 using nitrocefin substrate pre-incubated for 5 mins before substrate addition |
J Med Chem 59: 5542-54 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00660 BindingDB Entry DOI: 10.7270/Q2NP26CK |
More data for this Ligand-Target Pair | |
Regulatory protein E2
(Human papillomavirus type 16) | BDBM50060966
(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)Show InChI InChI=1S/C13H10O3/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9H,(H,14,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 9.10E+6 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Dissociation constant after binding to human papillomavirus E2 DNA-binding domain (DBD) by observing the changes in [15N]-HSQC spectra. |
J Med Chem 40: 3144-50 (1997)
Article DOI: 10.1021/jm9703404 BindingDB Entry DOI: 10.7270/Q2MG7NN2 |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Klebsiella pneumoniae) | BDBM50060966
(4-Phenoxy-benzoic acid | CHEMBL107518 | US10322118...)Show InChI InChI=1S/C13H10O3/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9H,(H,14,15) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 6.60E+5 | n/a | n/a | n/a | n/a | n/a |
UiT The Arctic University of Norway
Curated by ChEMBL
| Assay Description Binding affinity to native signal deficient and TEV cleavage site containing His-tagged Klebsiella pneumoniae OXA-48 expressed in Escherichia coli as... |
J Med Chem 59: 5542-54 (2016)
Article DOI: 10.1021/acs.jmedchem.6b00660 BindingDB Entry DOI: 10.7270/Q2NP26CK |
More data for this Ligand-Target Pair | |