Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50468868
(CHEMBL4290525)Show SMILES OC(=O)c1ccc(cc1)N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H21NO4S/c28-26(29)23-11-15-24(16-12-23)27(19-20-7-3-1-4-8-20)32(30,31)25-17-13-22(14-18-25)21-9-5-2-6-10-21/h1-18H,19H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe-University Frankfurt
Curated by ChEMBL
| Assay Description
Inhibition of 5-LO in human neutrophils using arachidonic acid as substrate assessed as reduction in 5-LO product formation preincubated for 15 mins ... |
Eur J Med Chem 156: 815-830 (2018)
Article DOI: 10.1016/j.ejmech.2018.07.031
BindingDB Entry DOI: 10.7270/Q2M61NXM |
More data for this
Ligand-Target Pair | |
Prostaglandin E synthase
(Homo sapiens (Human)) | BDBM50468868
(CHEMBL4290525)Show SMILES OC(=O)c1ccc(cc1)N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H21NO4S/c28-26(29)23-11-15-24(16-12-23)27(19-20-7-3-1-4-8-20)32(30,31)25-17-13-22(14-18-25)21-9-5-2-6-10-21/h1-18H,19H2,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Goethe-University Frankfurt
Curated by ChEMBL
| Assay Description
Inhibition of mPGES-1 isolated from microsomes of interleukin-1 beta-stimulated human A549 cells using PGH2 as substrate preincubated for 15 mins fol... |
Eur J Med Chem 156: 815-830 (2018)
Article DOI: 10.1016/j.ejmech.2018.07.031
BindingDB Entry DOI: 10.7270/Q2M61NXM |
More data for this
Ligand-Target Pair | |