Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cysteinyl leukotriene receptor 1
(Homo sapiens (Human)) | BDBM50057238
(2-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-pheny...)Show SMILES OC(=O)c1cccc(C(=O)\C=C\c2cccc(OCc3ccc4ccccc4n3)c2)c1O Show InChI InChI=1S/C26H19NO5/c28-24(21-8-4-9-22(25(21)29)26(30)31)14-11-17-5-3-7-20(15-17)32-16-19-13-12-18-6-1-2-10-23(18)27-19/h1-15,29H,16H2,(H,30,31)/b14-11+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 415 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhejiang University
Curated by ChEMBL
| Assay Description
Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L... |
Bioorg Med Chem 18: 5519-27 (2010)
Article DOI: 10.1016/j.bmc.2010.06.047
BindingDB Entry DOI: 10.7270/Q26D5TZ0 |
More data for this
Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1/2
(Homo sapiens (Human)) | BDBM50057238
(2-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-pheny...)Show SMILES OC(=O)c1cccc(C(=O)\C=C\c2cccc(OCc3ccc4ccccc4n3)c2)c1O Show InChI InChI=1S/C26H19NO5/c28-24(21-8-4-9-22(25(21)29)26(30)31)14-11-17-5-3-7-20(15-17)32-16-19-13-12-18-6-1-2-10-23(18)27-19/h1-15,29H,16H2,(H,30,31)/b14-11+ | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 415 | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit
Curated by ChEMBL
| Assay Description
Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes |
J Med Chem 40: 1075-89 (1997)
Article DOI: 10.1021/jm960628d
BindingDB Entry DOI: 10.7270/Q25141XJ |
More data for this
Ligand-Target Pair | |