Found 8 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein kinase C delta type
(Homo sapiens (Human)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |
Protein kinase C beta type
(Homo sapiens (Human)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |
Protein kinase C eta type
(Homo sapiens (Human)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |
Protein kinase C gamma type
(Homo sapiens (Human)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |
Protein kinase C beta type
(Homo sapiens (Human)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |
Protein kinase C epsilon type
(Homo sapiens (Human)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |
Protein kinase C alpha type
(Homo sapiens (Human)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |
cAMP-dependent protein kinase catalytic subunit alpha
(Bos taurus (bovine)) | BDBM3196
((+-)-2-[[2,6-Dihydroxy-4-[[2-(4-hydroxyphenyl)-2-[...)Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)OCC(NS(=O)(=O)c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C29H23NO11S/c31-18-11-9-16(10-12-18)21(30-42(39,40)19-5-2-1-3-6-19)15-41-29(38)17-13-23(33)26(24(34)14-17)27(35)25-20(28(36)37)7-4-8-22(25)32/h1-14,21,30-34H,15H2,(H,36,37) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sphinx Laboratories
| Assay Description The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone. |
J Med Chem 39: 5215-27 (1996)
Article DOI: 10.1021/jm960581w BindingDB Entry DOI: 10.7270/Q2G73BVV |
More data for this Ligand-Target Pair | |