Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 445.4 BDBM50535032

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50535032 (CHEMBL4467142) Show SMILES OC(=O)c1cccc(c1)[C@H]1C[C@H](CCO1)NC(=O)C1(CC1)c1ccc2OC(F)(F)Oc2c1 |r| Show InChI InChI=1S/C23H21F2NO6/c24-23(25)31-17-5-4-15(11-19(17)32-23)22(7-8-22)21(29)26-16-6-9-30-18(12-16)13-2-1-3-14(10-13)20(27)28/h1-5,10-11,16,18H,6-9,12H2,(H,26,29)(H,27,28)/t16-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	850	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Corrector activity at CFTR F508del mutant (unknown origin) expressed in human CFBE41o cells incubated for 18 to 24 hrs by CSE-HRP assay				ACS Med Chem Lett 7: 725-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00258 BindingDB Entry DOI: 10.7270/Q2S1860M
					More data for this Ligand-Target Pair