Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372371
(CHEMBL271789)Show SMILES OC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H18N2O5/c27-21(23-25-15-22(31-23)19-7-4-8-20(26-19)24(28)29)14-11-16-9-12-18(13-10-16)30-17-5-2-1-3-6-17/h1-10,12-13,15H,11,14H2,(H,28,29) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372371
(CHEMBL271789)Show SMILES OC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H18N2O5/c27-21(23-25-15-22(31-23)19-7-4-8-20(26-19)24(28)29)14-11-16-9-12-18(13-10-16)30-17-5-2-1-3-6-17/h1-10,12-13,15H,11,14H2,(H,28,29) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Liver carboxylesterase 1
(Homo sapiens (Human)) | BDBM50372371
(CHEMBL271789)Show SMILES OC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H18N2O5/c27-21(23-25-15-22(31-23)19-7-4-8-20(26-19)24(28)29)14-11-16-9-12-18(13-10-16)30-17-5-2-1-3-6-17/h1-10,12-13,15H,11,14H2,(H,28,29) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of TGH |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human)) | BDBM50372371
(CHEMBL271789)Show SMILES OC(=O)c1cccc(n1)-c1cnc(o1)C(=O)CCc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C24H18N2O5/c27-21(23-25-15-22(31-23)19-7-4-8-20(26-19)24(28)29)14-11-16-9-12-18(13-10-16)30-17-5-2-1-3-6-17/h1-10,12-13,15H,11,14H2,(H,28,29) | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of KIAA1363 |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |