Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 382.4 BDBM50313721

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bombesin receptor subtype-3 (Mus musculus)	BDBM50313721 (4'-(2-(5-benzyl-1H-imidazol-2-yl)ethyl)biphenyl-2-...) Show SMILES OC(=O)c1ccccc1-c1ccc(CCc2ncc(Cc3ccccc3)[nH]2)cc1 Show InChI InChI=1S/C25H22N2O2/c28-25(29)23-9-5-4-8-22(23)20-13-10-18(11-14-20)12-15-24-26-17-21(27-24)16-19-6-2-1-3-7-19/h1-11,13-14,17H,12,15-16H2,(H,26,27)(H,28,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity at mouse BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 1913-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.154 BindingDB Entry DOI: 10.7270/Q2M045KD
					More data for this Ligand-Target Pair
Bombesin receptor subtype-3 (Homo sapiens (Human))	BDBM50313721 (4'-(2-(5-benzyl-1H-imidazol-2-yl)ethyl)biphenyl-2-...) Show SMILES OC(=O)c1ccccc1-c1ccc(CCc2ncc(Cc3ccccc3)[nH]2)cc1 Show InChI InChI=1S/C25H22N2O2/c28-25(29)23-9-5-4-8-22(23)20-13-10-18(11-14-20)12-15-24-26-17-21(27-24)16-19-6-2-1-3-7-19/h1-11,13-14,17H,12,15-16H2,(H,26,27)(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	205	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonistic activity at human BRS3 expressed in HEK293AEO cells by aequorin bioluminescence assay				Bioorg Med Chem Lett 20: 1913-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.154 BindingDB Entry DOI: 10.7270/Q2M045KD
					More data for this Ligand-Target Pair