Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 409.4 BDBM50057225

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50057225 (2-(3-(3-(quinolin-2-ylmethoxy)phenyl)acryloyl)benz...) Show SMILES OC(=O)c1ccccc1C(=O)\C=C\c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C26H19NO4/c28-25(22-9-2-3-10-23(22)26(29)30)15-12-18-6-5-8-21(16-18)31-17-20-14-13-19-7-1-4-11-24(19)27-20/h1-16H,17H2,(H,29,30)/b15-12+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50057225 (2-(3-(3-(quinolin-2-ylmethoxy)phenyl)acryloyl)benz...) Show SMILES OC(=O)c1ccccc1C(=O)\C=C\c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C26H19NO4/c28-25(22-9-2-3-10-23(22)26(29)30)15-12-18-6-5-8-21(16-18)31-17-20-14-13-19-7-1-4-11-24(19)27-20/h1-16H,17H2,(H,29,30)/b15-12+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 40: 1075-89 (1997) Article DOI: 10.1021/jm960628d BindingDB Entry DOI: 10.7270/Q25141XJ
					More data for this Ligand-Target Pair