Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 370.4 BDBM50006798Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50006798 (2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...) Show SMILES OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Rorer Central Research Curated by ChEMBL					Assay Description Inhibitory concentration of compound against binding of Cysteinyl leukotriene D4 receptor from guinea pig lung using [3H]-LTD4				J Med Chem 33: 1194-200 (1990) BindingDB Entry DOI: 10.7270/Q2PK0F4V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50006798 (2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...) Show SMILES OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound was tested for inhibitory activity against LTD4 (leukotriene).				J Med Chem 39: 2629-54 (1996) Article DOI: 10.1021/jm960088k BindingDB Entry DOI: 10.7270/Q21J9BFT
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50006798 (2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...) Show SMILES OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 34: 1235-42 (1991) BindingDB Entry DOI: 10.7270/Q2K936HB
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006798 (2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...) Show SMILES OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description The compound was tested for inhibitory activity against Prostaglandin G/H synthase in rat polymorphonuclear leukocytes[PMNS]				J Med Chem 35: 2501-24 (1992) BindingDB Entry DOI: 10.7270/Q23B60R4
					More data for this Ligand-Target Pair
Huntingtin (Homo sapiens (Human))	BDBM50006798 (2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...) Show SMILES OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PCBioAssay	n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2N58K09
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006798 (2-[3-(Quinolin-2-ylmethoxy)-phenylamino]-benzoic a...) Show SMILES OC(=O)c1ccccc1Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description The compound was tested for inhibitory activity against 5-lipoxygenase in rat polymorphonuclear leukocytes[PMNS]				J Med Chem 35: 2501-24 (1992) BindingDB Entry DOI: 10.7270/Q23B60R4
					More data for this Ligand-Target Pair