Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50364017
(CHEMBL1950405)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nc1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C22H19BrFN3O3/c23-19-3-2-17(24)10-20(19)30-18-5-7-27(8-6-18)21-4-1-14(13-26-21)15-9-16(22(28)29)12-25-11-15/h1-4,9-13,18H,5-8H2,(H,28,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50364017
(CHEMBL1950405)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nc1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C22H19BrFN3O3/c23-19-3-2-17(24)10-20(19)30-18-5-7-27(8-6-18)21-4-1-14(13-26-21)15-9-16(22(28)29)12-25-11-15/h1-4,9-13,18H,5-8H2,(H,28,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in Sprague-Dawley rat hepatocytes assessed as conversion of [14C]oleic acid formation by HPLC analysis |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50364017
(CHEMBL1950405)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nc1)N1CCC(CC1)Oc1cc(F)ccc1Br Show InChI InChI=1S/C22H19BrFN3O3/c23-19-3-2-17(24)10-20(19)30-18-5-7-27(8-6-18)21-4-1-14(13-26-21)15-9-16(22(28)29)12-25-11-15/h1-4,9-13,18H,5-8H2,(H,28,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 expressed in human HepG2 cells assessed as conversion of [14C]stearic acid to [14C]oleic acid |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |