Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50364011
(CHEMBL1950396)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)c(F)cc1Br Show InChI InChI=1S/C21H17BrF2N4O3/c22-15-8-16(23)17(24)9-19(15)31-14-3-5-28(6-4-14)20-2-1-18(26-27-20)12-7-13(21(29)30)11-25-10-12/h1-2,7-11,14H,3-6H2,(H,29,30) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50364011
(CHEMBL1950396)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)c(F)cc1Br Show InChI InChI=1S/C21H17BrF2N4O3/c22-15-8-16(23)17(24)9-19(15)31-14-3-5-28(6-4-14)20-2-1-18(26-27-20)12-7-13(21(29)30)11-25-10-12/h1-2,7-11,14H,3-6H2,(H,29,30) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 563 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in Sprague-Dawley rat hepatocytes assessed as conversion of [14C]oleic acid formation by HPLC analysis |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50364011
(CHEMBL1950396)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)c(F)cc1Br Show InChI InChI=1S/C21H17BrF2N4O3/c22-15-8-16(23)17(24)9-19(15)31-14-3-5-28(6-4-14)20-2-1-18(26-27-20)12-7-13(21(29)30)11-25-10-12/h1-2,7-11,14H,3-6H2,(H,29,30) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 expressed in human HepG2 cells assessed as conversion of [14C]stearic acid to [14C]oleic acid |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |