Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50364022
(CHEMBL1950395)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1I Show InChI InChI=1S/C21H19IN4O3/c22-17-3-1-2-4-19(17)29-16-7-9-26(10-8-16)20-6-5-18(24-25-20)14-11-15(21(27)28)13-23-12-14/h1-6,11-13,16H,7-10H2,(H,27,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of rat SCD1 |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Rattus norvegicus (Rat)) | BDBM50364022
(CHEMBL1950395)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1I Show InChI InChI=1S/C21H19IN4O3/c22-17-3-1-2-4-19(17)29-16-7-9-26(10-8-16)20-6-5-18(24-25-20)14-11-15(21(27)28)13-23-12-14/h1-6,11-13,16H,7-10H2,(H,27,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in Sprague-Dawley rat hepatocytes assessed as conversion of [14C]oleic acid formation by HPLC analysis |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50364022
(CHEMBL1950395)Show SMILES OC(=O)c1cncc(c1)-c1ccc(nn1)N1CCC(CC1)Oc1ccccc1I Show InChI InChI=1S/C21H19IN4O3/c22-17-3-1-2-4-19(17)29-16-7-9-26(10-8-16)20-6-5-18(24-25-20)14-11-15(21(27)28)13-23-12-14/h1-6,11-13,16H,7-10H2,(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research
Curated by ChEMBL
| Assay Description
Inhibition of human SCD1 expressed in human HepG2 cells assessed as conversion of [14C]stearic acid to [14C]oleic acid |
Bioorg Med Chem Lett 21: 7281-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.040
BindingDB Entry DOI: 10.7270/Q2G44QQZ |
More data for this
Ligand-Target Pair | |