Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50304947
(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC(CC1)C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H26N4O3/c30-22(18-7-3-1-4-8-18)17-26-25(32)21-11-12-23(28-27-21)29-15-13-20(14-16-29)24(31)19-9-5-2-6-10-19/h1-12,20,22,30H,13-17H2,(H,26,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human Scd1 expressed in HEK-293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 h... |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50304947
(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC(CC1)C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H26N4O3/c30-22(18-7-3-1-4-8-18)17-26-25(32)21-11-12-23(28-27-21)29-15-13-20(14-16-29)24(31)19-9-5-2-6-10-19/h1-12,20,22,30H,13-17H2,(H,26,32) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 153 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50304947
(6-(4-benzoylpiperidin-1-yl)-N-(2-hydroxy-2-phenyle...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC(CC1)C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H26N4O3/c30-22(18-7-3-1-4-8-18)17-26-25(32)21-11-12-23(28-27-21)29-15-13-20(14-16-29)24(31)19-9-5-2-6-10-19/h1-12,20,22,30H,13-17H2,(H,26,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 292 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Scd1 in human HEK-293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 ... |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |