Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50304946
(CHEMBL600052 | N-(2-hydroxy-2-phenylethyl)-6-(4-(3...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC(CC1)C(=O)c1ccccc1OC(F)(F)F)c1ccccc1 Show InChI InChI=1S/C26H25F3N4O4/c27-26(28,29)37-22-9-5-4-8-19(22)24(35)18-12-14-33(15-13-18)23-11-10-20(31-32-23)25(36)30-16-21(34)17-6-2-1-3-7-17/h1-11,18,21,34H,12-16H2,(H,30,36) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Scd1 in mouse liver microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 mins |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50304946
(CHEMBL600052 | N-(2-hydroxy-2-phenylethyl)-6-(4-(3...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC(CC1)C(=O)c1ccccc1OC(F)(F)F)c1ccccc1 Show InChI InChI=1S/C26H25F3N4O4/c27-26(28,29)37-22-9-5-4-8-19(22)24(35)18-12-14-33(15-13-18)23-11-10-20(31-32-23)25(36)30-16-21(34)17-6-2-1-3-7-17/h1-11,18,21,34H,12-16H2,(H,30,36) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of Scd1 in human HEK-293A cell microsomes assessed as conversion of [14C]stearate to [14C]oleate pretreated for 10 mins measured after 60 ... |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50304946
(CHEMBL600052 | N-(2-hydroxy-2-phenylethyl)-6-(4-(3...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC(CC1)C(=O)c1ccccc1OC(F)(F)F)c1ccccc1 Show InChI InChI=1S/C26H25F3N4O4/c27-26(28,29)37-22-9-5-4-8-19(22)24(35)18-12-14-33(15-13-18)23-11-10-20(31-32-23)25(36)30-16-21(34)17-6-2-1-3-7-17/h1-11,18,21,34H,12-16H2,(H,30,36) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human Scd1 expressed in HEK-293A cells assessed as conversion of [14C]stearate to [14C]oleate pretreated for 30 mins measured after 4 h... |
Bioorg Med Chem Lett 20: 341-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.101
BindingDB Entry DOI: 10.7270/Q23X86R7 |
More data for this
Ligand-Target Pair | |