Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50306121
(6-(8-fluoro-4-hydroxyspiro[chroman-2,4'-piperidine...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC2(CC1)CC(O)c1cccc(F)c1O2)c1ccccc1 Show InChI InChI=1S/C26H27FN4O4/c27-19-8-4-7-18-21(32)15-26(35-24(18)19)11-13-31(14-12-26)23-10-9-20(29-30-23)25(34)28-16-22(33)17-5-2-1-3-6-17/h1-10,21-22,32-33H,11-16H2,(H,28,34) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in human 293A cells assessed as conversion of [14C]stearate to [14C]oleate after 60 mins in presence of S9 microsomal fraction |
Bioorg Med Chem Lett 20: 746-54 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.043
BindingDB Entry DOI: 10.7270/Q28C9WBJ |
More data for this
Ligand-Target Pair | |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50306121
(6-(8-fluoro-4-hydroxyspiro[chroman-2,4'-piperidine...)Show SMILES OC(CNC(=O)c1ccc(nn1)N1CCC2(CC1)CC(O)c1cccc(F)c1O2)c1ccccc1 Show InChI InChI=1S/C26H27FN4O4/c27-19-8-4-7-18-21(32)15-26(35-24(18)19)11-13-31(14-12-26)23-10-9-20(29-30-23)25(34)28-16-22(33)17-5-2-1-3-6-17/h1-10,21-22,32-33H,11-16H2,(H,28,34) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 315 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of SCD1 in mouse microsomal liver S9 microsomal fraction assessed as conversion of [14C]stearate to [14C]oleate after 60 mins |
Bioorg Med Chem Lett 20: 746-54 (2010)
Article DOI: 10.1016/j.bmcl.2009.11.043
BindingDB Entry DOI: 10.7270/Q28C9WBJ |
More data for this
Ligand-Target Pair | |