Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50027881
(CHEMBL2348207)Show SMILES OC(CNCCNC(=O)Nc1cccc(c1)C(F)(F)F)COc1ccc(OCCOC2CCCC2)cc1 Show InChI InChI=1S/C26H34F3N3O5/c27-26(28,29)19-4-3-5-20(16-19)32-25(34)31-13-12-30-17-21(33)18-37-24-10-8-23(9-11-24)36-15-14-35-22-6-1-2-7-22/h3-5,8-11,16,21-22,30,33H,1-2,6-7,12-15,17-18H2,(H2,31,32,34) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.38E+3 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CGP12177 from human beta2 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis |
J Med Chem 56: 3852-65 (2013)
Article DOI: 10.1021/jm400348g
BindingDB Entry DOI: 10.7270/Q2445NV6 |
More data for this
Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50027881
(CHEMBL2348207)Show SMILES OC(CNCCNC(=O)Nc1cccc(c1)C(F)(F)F)COc1ccc(OCCOC2CCCC2)cc1 Show InChI InChI=1S/C26H34F3N3O5/c27-26(28,29)19-4-3-5-20(16-19)32-25(34)31-13-12-30-17-21(33)18-37-24-10-8-23(9-11-24)36-15-14-35-22-6-1-2-7-22/h3-5,8-11,16,21-22,30,33H,1-2,6-7,12-15,17-18H2,(H2,31,32,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description
Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis |
J Med Chem 56: 3852-65 (2013)
Article DOI: 10.1021/jm400348g
BindingDB Entry DOI: 10.7270/Q2445NV6 |
More data for this
Ligand-Target Pair | |