Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50027874
(CHEMBL2348203)Show SMILES OC(CNCCNC(=O)Nc1ccccc1Br)COc1ccc(OCCOC2CCCC2)cc1 Show InChI InChI=1S/C25H34BrN3O5/c26-23-7-3-4-8-24(23)29-25(31)28-14-13-27-17-19(30)18-34-22-11-9-21(10-12-22)33-16-15-32-20-5-1-2-6-20/h3-4,7-12,19-20,27,30H,1-2,5-6,13-18H2,(H2,28,29,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 794 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Displacement of [3H]-CGP12177 from human beta2 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis |
J Med Chem 56: 3852-65 (2013)
Article DOI: 10.1021/jm400348g BindingDB Entry DOI: 10.7270/Q2445NV6 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50027874
(CHEMBL2348203)Show SMILES OC(CNCCNC(=O)Nc1ccccc1Br)COc1ccc(OCCOC2CCCC2)cc1 Show InChI InChI=1S/C25H34BrN3O5/c26-23-7-3-4-8-24(23)29-25(31)28-14-13-27-17-19(30)18-34-22-11-9-21(10-12-22)33-16-15-32-20-5-1-2-6-20/h3-4,7-12,19-20,27,30H,1-2,5-6,13-18H2,(H2,28,29,31) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham
Curated by ChEMBL
| Assay Description Displacement of [3H]-CGP12177 from human beta1 adrenoceptor expressed in CHOK1 cells after 2 hrs by scintillation counting analysis |
J Med Chem 56: 3852-65 (2013)
Article DOI: 10.1021/jm400348g BindingDB Entry DOI: 10.7270/Q2445NV6 |
More data for this Ligand-Target Pair | |