Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 379.2 BDBM50367122

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50367122 (CHEMBL4164293) Show SMILES OC(c1ccc2[nH]c(=O)c3c(F)cccc3c2c1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C16H8F7NO2/c17-10-3-1-2-8-9-6-7(4-5-11(9)24-13(25)12(8)10)14(26,15(18,19)20)16(21,22)23/h1-6,26H,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity measured after 24 hrs				ACS Med Chem Lett 9: 641-645 (2018) Article DOI: 10.1021/acsmedchemlett.8b00058 BindingDB Entry DOI: 10.7270/Q2PN986S
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