Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 287.1 BDBM408863

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Asialoglycoprotein receptor 1 (Homo sapiens (Human))	BDBM408863 (US10376531, Compound 24 | US10813942, Compound 24) Show SMILES OC[C@@]12CO[C@@H](O1)[C@H](NC(=O)C(F)(F)F)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C9H12F3NO6/c10-9(11,12)7(17)13-3-4(15)5(16)8(1-14)2-18-6(3)19-8/h3-6,14-16H,1-2H2,(H,13,17)/t3-,4-,5-,6?,8+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...				US Patent US10813942 (2020) BindingDB Entry DOI: 10.7270/Q28G8PSJ
					More data for this Ligand-Target Pair
Asialoglycoprotein receptor 1 (Homo sapiens (Human))	BDBM408863 (US10376531, Compound 24 | US10813942, Compound 24) Show SMILES OC[C@@]12CO[C@@H](O1)[C@H](NC(=O)C(F)(F)F)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C9H12F3NO6/c10-9(11,12)7(17)13-3-4(15)5(16)8(1-14)2-18-6(3)19-8/h3-6,14-16H,1-2H2,(H,13,17)/t3-,4-,5-,6?,8+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...				US Patent US10376531 (2019) BindingDB Entry DOI: 10.7270/Q2542QZJ
					More data for this Ligand-Target Pair