Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Asialoglycoprotein receptor 1
(Homo sapiens (Human)) | BDBM408867
(US10376531, Compound 27 | US10813942, Compound 27)Show SMILES OC[C@@]12CO[C@@H](O1)[C@H](NC(=O)C(F)F)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C9H13F2NO6/c10-6(11)7(16)12-3-4(14)5(15)9(1-13)2-17-8(3)18-9/h3-6,8,13-15H,1-2H2,(H,12,16)/t3-,4-,5-,8?,9+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200... |
US Patent US10813942 (2020)
BindingDB Entry DOI: 10.7270/Q28G8PSJ |
More data for this Ligand-Target Pair | |
Asialoglycoprotein receptor 1
(Homo sapiens (Human)) | BDBM408867
(US10376531, Compound 27 | US10813942, Compound 27)Show SMILES OC[C@@]12CO[C@@H](O1)[C@H](NC(=O)C(F)F)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C9H13F2NO6/c10-6(11)7(16)12-3-4(14)5(15)9(1-13)2-17-8(3)18-9/h3-6,8,13-15H,1-2H2,(H,12,16)/t3-,4-,5-,8?,9+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200... |
US Patent US10376531 (2019)
BindingDB Entry DOI: 10.7270/Q2542QZJ |
More data for this Ligand-Target Pair | |