Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 301.2 BDBM408868

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Asialoglycoprotein receptor 1 (Homo sapiens (Human))	BDBM408868 (US10376531, Compound 28 | US10813942, Compound 28) Show SMILES OC[C@@]12CO[C@@H](O1)[C@H](NC(=O)CC(F)(F)F)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C10H14F3NO6/c11-10(12,13)1-4(16)14-5-6(17)7(18)9(2-15)3-19-8(5)20-9/h5-8,15,17-18H,1-3H2,(H,14,16)/t5-,6-,7-,8?,9+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...				US Patent US10813942 (2020) BindingDB Entry DOI: 10.7270/Q28G8PSJ
					More data for this Ligand-Target Pair
Asialoglycoprotein receptor 1 (Homo sapiens (Human))	BDBM408868 (US10376531, Compound 28 | US10813942, Compound 28) Show SMILES OC[C@@]12CO[C@@H](O1)[C@H](NC(=O)CC(F)(F)F)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C10H14F3NO6/c11-10(12,13)1-4(16)14-5-6(17)7(18)9(2-15)3-19-8(5)20-9/h5-8,15,17-18H,1-3H2,(H,14,16)/t5-,6-,7-,8?,9+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...				US Patent US10376531 (2019) BindingDB Entry DOI: 10.7270/Q2542QZJ
					More data for this Ligand-Target Pair