Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50065422
((R)-2-(4-Fluoro-phenyl)-2-{1-[2-fluoro-3-(5-[1,2,4...)Show SMILES OC[C@H](NC1CCN(CC(F)Cc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H30F2N6O/c27-20-3-1-18(2-4-20)26(15-35)32-22-7-9-33(10-8-22)14-21(28)11-19-13-29-25-6-5-23(12-24(19)25)34-16-30-31-17-34/h1-6,12-13,16-17,21-22,26,29,32,35H,7-11,14-15H2/t21?,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description
Displacement of [3H]-5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cells |
J Med Chem 41: 2667-70 (1998)
Article DOI: 10.1021/jm980204e
BindingDB Entry DOI: 10.7270/Q22Z14PW |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50065422
((R)-2-(4-Fluoro-phenyl)-2-{1-[2-fluoro-3-(5-[1,2,4...)Show SMILES OC[C@H](NC1CCN(CC(F)Cc2c[nH]c3ccc(cc23)-n2cnnc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H30F2N6O/c27-20-3-1-18(2-4-20)26(15-35)32-22-7-9-33(10-8-22)14-21(28)11-19-13-29-25-6-5-23(12-24(19)25)34-16-30-31-17-34/h1-6,12-13,16-17,21-22,26,29,32,35H,7-11,14-15H2/t21?,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories
Curated by ChEMBL
| Assay Description
Agonist induced [35S]-GTP-gammaS, binding in CHO cells expressing 5-HT 1d receptor |
J Med Chem 41: 2667-70 (1998)
Article DOI: 10.1021/jm980204e
BindingDB Entry DOI: 10.7270/Q22Z14PW |
More data for this
Ligand-Target Pair | |