Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440953
(US10639284, Compound 3.122 | US11426364, Compound ...)Show SMILES OC[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccc3OCOc3c2)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C33H28ClN3O7/c34-26-9-22(15-37-27(16-38)33(39)40)30(41-17-20-8-19(12-35)13-36-14-20)11-31(26)44-28-7-5-24-23(2-1-3-25(24)28)21-4-6-29-32(10-21)43-18-42-29/h1-4,6,8-11,13-14,27-28,37-38H,5,7,15-18H2,(H,39,40)/t27-,28-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2K93BSK |
More data for this
Ligand-Target Pair | |
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440953
(US10639284, Compound 3.122 | US11426364, Compound ...)Show SMILES OC[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccc3OCOc3c2)cc1OCc1cncc(c1)C#N)C(O)=O |r| Show InChI InChI=1S/C33H28ClN3O7/c34-26-9-22(15-37-27(16-38)33(39)40)30(41-17-20-8-19(12-35)13-36-14-20)11-31(26)44-28-7-5-24-23(2-1-3-25(24)28)21-4-6-29-32(10-21)43-18-42-29/h1-4,6,8-11,13-14,27-28,37-38H,5,7,15-18H2,(H,39,40)/t27-,28-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA... |
US Patent US10639284 (2020)
BindingDB Entry DOI: 10.7270/Q25Q5043 |
More data for this
Ligand-Target Pair | |