Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440835
(US10639284, Compound 3.004 | US11426364, Compound ...)Show SMILES OC[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccccc2F)cc1OCc1cc(cc(c1)C#N)C#N)C(O)=O |r| Show InChI InChI=1S/C34H27ClFN3O5/c35-28-13-23(17-39-30(18-40)34(41)42)32(43-19-22-11-20(15-37)10-21(12-22)16-38)14-33(28)44-31-9-8-25-24(5-3-6-27(25)31)26-4-1-2-7-29(26)36/h1-7,10-14,30-31,39-40H,8-9,17-19H2,(H,41,42)/t30-,31-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2K93BSK |
More data for this
Ligand-Target Pair | |
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440835
(US10639284, Compound 3.004 | US11426364, Compound ...)Show SMILES OC[C@H](NCc1cc(Cl)c(O[C@H]2CCc3c2cccc3-c2ccccc2F)cc1OCc1cc(cc(c1)C#N)C#N)C(O)=O |r| Show InChI InChI=1S/C34H27ClFN3O5/c35-28-13-23(17-39-30(18-40)34(41)42)32(43-19-22-11-20(15-37)10-21(12-22)16-38)14-33(28)44-31-9-8-25-24(5-3-6-27(25)31)26-4-1-2-7-29(26)36/h1-7,10-14,30-31,39-40H,8-9,17-19H2,(H,41,42)/t30-,31-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA... |
US Patent US10639284 (2020)
BindingDB Entry DOI: 10.7270/Q25Q5043 |
More data for this
Ligand-Target Pair | |