Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 303.3 BDBM50438506

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM50438506 (CHEMBL2414816) Show SMILES OC[C@H]1O[C@@H](CNC(=O)c2cccs2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C12H17NO6S/c14-5-7-10(16)11(17)9(15)6(19-7)4-13-12(18)8-2-1-3-20-8/h1-3,6-7,9-11,14-17H,4-5H2,(H,13,18)/t6-,7+,9-,10+,11+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...				Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24
					More data for this Ligand-Target Pair
Lysosomal alpha-glucosidase (Rattus norvegicus)	BDBM50438506 (CHEMBL2414816) Show SMILES OC[C@H]1O[C@@H](CNC(=O)c2cccs2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C12H17NO6S/c14-5-7-10(16)11(17)9(15)6(19-7)4-13-12(18)8-2-1-3-20-8/h1-3,6-7,9-11,14-17H,4-5H2,(H,13,18)/t6-,7+,9-,10+,11+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...				Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM50438506 (CHEMBL2414816) Show SMILES OC[C@H]1O[C@@H](CNC(=O)c2cccs2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C12H17NO6S/c14-5-7-10(16)11(17)9(15)6(19-7)4-13-12(18)8-2-1-3-20-8/h1-3,6-7,9-11,14-17H,4-5H2,(H,13,18)/t6-,7+,9-,10+,11+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...				Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24
					More data for this Ligand-Target Pair