Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM50374866
(CHEMBL270433)Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccc3ccccc23)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S/c25-21-11-9-20(10-12-21)24(28)13-17-27(18-14-24)16-4-15-26-31(29,30)23-8-3-6-19-5-1-2-7-22(19)23/h1-3,5-12,26,28H,4,13-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa... |
Bioorg Med Chem Lett 18: 2215-21 (2008)
Article DOI: 10.1016/j.bmcl.2007.09.068
BindingDB Entry DOI: 10.7270/Q21C1XQP |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM50374866
(CHEMBL270433)Show SMILES OC1(CCN(CCCNS(=O)(=O)c2cccc3ccccc23)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S/c25-21-11-9-20(10-12-21)24(28)13-17-27(18-14-24)16-4-15-26-31(29,30)23-8-3-6-19-5-1-2-7-22(19)23/h1-3,5-12,26,28H,4,13-18H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories USA, Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells |
Bioorg Med Chem Lett 18: 2215-21 (2008)
Article DOI: 10.1016/j.bmcl.2007.09.068
BindingDB Entry DOI: 10.7270/Q21C1XQP |
More data for this
Ligand-Target Pair | |