Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM50374822
(CHEMBL257452)Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2-c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S2/c25-20-10-8-19(9-11-20)24(28)12-16-27(17-13-24)15-4-14-26-32(29,30)23-7-2-1-5-21(23)22-6-3-18-31-22/h1-3,5-11,18,26,28H,4,12-17H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories USA, Inc.
Curated by ChEMBL
| Assay Description
Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa... |
Bioorg Med Chem Lett 18: 2215-21 (2008)
Article DOI: 10.1016/j.bmcl.2007.09.068
BindingDB Entry DOI: 10.7270/Q21C1XQP |
More data for this
Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM50374822
(CHEMBL257452)Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2-c2cccs2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27ClN2O3S2/c25-20-10-8-19(9-11-20)24(28)12-16-27(17-13-24)15-4-14-26-32(29,30)23-7-2-1-5-21(23)22-6-3-18-31-22/h1-3,5-11,18,26,28H,4,12-17H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Research Laboratories USA, Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells |
Bioorg Med Chem Lett 18: 2215-21 (2008)
Article DOI: 10.1016/j.bmcl.2007.09.068
BindingDB Entry DOI: 10.7270/Q21C1XQP |
More data for this
Ligand-Target Pair | |