Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440719
(US10639284, Compound 2.070 | US11426364, Compound ...)Show SMILES OC1CN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3ccc4OCCOc4c3F)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C34H29ClFN3O5/c35-28-11-22(16-39-17-23(40)18-39)31(43-19-21-10-20(13-37)14-38-15-21)12-32(28)44-29-6-4-25-24(2-1-3-26(25)29)27-5-7-30-34(33(27)36)42-9-8-41-30/h1-3,5,7,10-12,14-15,23,29,40H,4,6,8-9,16-19H2/t29-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2K93BSK |
More data for this
Ligand-Target Pair | |
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM440719
(US10639284, Compound 2.070 | US11426364, Compound ...)Show SMILES OC1CN(Cc2cc(Cl)c(O[C@H]3CCc4c3cccc4-c3ccc4OCCOc4c3F)cc2OCc2cncc(c2)C#N)C1 |r| Show InChI InChI=1S/C34H29ClFN3O5/c35-28-11-22(16-39-17-23(40)18-39)31(43-19-21-10-20(13-37)14-38-15-21)12-32(28)44-29-6-4-25-24(2-1-3-26(25)29)27-5-7-30-34(33(27)36)42-9-8-41-30/h1-3,5,7,10-12,14-15,23,29,40H,4,6,8-9,16-19H2/t29-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with PBS containing 2% BSA... |
US Patent US10639284 (2020)
BindingDB Entry DOI: 10.7270/Q25Q5043 |
More data for this
Ligand-Target Pair | |