Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 282.2 BDBM380977

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM380977 (2-(4-Hydroxy-3,4-dihydro-1H- pyrano[4,3-c]pyridin-...) Show SMILES OC1COCc2c1cncc2-c1ccc2C(=O)CCc2n1 Show InChI InChI=1S/C16H14N2O3/c19-15-4-3-13-9(15)1-2-14(18-13)10-5-17-6-11-12(10)7-21-8-16(11)20/h1-2,5-6,16,20H,3-4,7-8H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondria...				Bioorg Med Chem Lett 18: 1274-9 (2008) BindingDB Entry DOI: 10.7270/Q2K35WZ4
					More data for this Ligand-Target Pair