Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Interleukin-1 receptor-associated kinase 4
(Homo sapiens (Human)) | BDBM271362
(US10064861, Compound 17)Show SMILES OC1Cn2c(NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cccc1c4)c3)nc1ccccc21 Show InChI InChI=1S/C27H21N5O3/c33-24-16-31-23-10-2-1-9-22(23)28-27(31)29-26(35)20-8-3-5-17(13-20)15-32-25(34)12-11-21(30-32)18-6-4-7-19(24)14-18/h1-14,24,33H,15-16H2,(H,28,29,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Merck Patent GmbH
US Patent
| Assay Description
IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712) IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine ... |
US Patent US10064861 (2018)
BindingDB Entry DOI: 10.7270/Q2NV9M8K |
More data for this
Ligand-Target Pair | |
Interleukin-1 receptor-associated kinase 1
(Homo sapiens (Human)) | BDBM271362
(US10064861, Compound 17)Show SMILES OC1Cn2c(NC(=O)c3cccc(Cn4nc(ccc4=O)-c4cccc1c4)c3)nc1ccccc21 Show InChI InChI=1S/C27H21N5O3/c33-24-16-31-23-10-2-1-9-22(23)28-27(31)29-26(35)20-8-3-5-17(13-20)15-32-25(34)12-11-21(30-32)18-6-4-7-19(24)14-18/h1-14,24,33H,15-16H2,(H,28,29,35) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Merck Patent GmbH
US Patent
| Assay Description
IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)) In this assay, IRAK-1 hydrolyses ATP and autophosphorylates.Measurement of IRA... |
US Patent US10064861 (2018)
BindingDB Entry DOI: 10.7270/Q2NV9M8K |
More data for this
Ligand-Target Pair | |