Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 251.2 BDBM378532

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM378532 (1-cyclopropyl-N-[1-(2-hydroxyethyl)azetidin-3-yl]-...) Show SMILES OCCN1CC(C1)NC(=O)c1cn(nn1)C1CC1 Show InChI InChI=1S/C11H17N5O2/c17-4-3-15-5-8(6-15)12-11(18)10-7-16(14-13-10)9-1-2-9/h7-9,17H,1-6H2,(H,12,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
ENSCMu					Assay Description The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...				Bioorg Med Chem 14: 7241-57 (2006) BindingDB Entry DOI: 10.7270/Q2DJ5HX2
					More data for this Ligand-Target Pair