Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296310
(3-(2-hydroxyethoxy)-4-morpholino-N-(5-(3-(trifluor...)Show SMILES OCCOc1cc(ccc1N1CCOCC1)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C24H24F3N3O4S/c25-24(26,27)18-3-1-2-16(12-18)13-19-15-28-23(35-19)29-22(32)17-4-5-20(21(14-17)34-11-8-31)30-6-9-33-10-7-30/h1-5,12,14-15,31H,6-11,13H2,(H,28,29,32) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123 BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296310
(3-(2-hydroxyethoxy)-4-morpholino-N-(5-(3-(trifluor...)Show SMILES OCCOc1cc(ccc1N1CCOCC1)C(=O)Nc1ncc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C24H24F3N3O4S/c25-24(26,27)18-3-1-2-16(12-18)13-19-15-28-23(35-19)29-22(32)17-4-5-20(21(14-17)34-11-8-31)30-6-9-33-10-7-30/h1-5,12,14-15,31H,6-11,13H2,(H,28,29,32) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123 BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this Ligand-Target Pair | |