Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neprilysin
(Rattus norvegicus (Rat)) | BDBM50085454
(CHEMBL90388 | N-formyl hydroxylamine containing di...)Show SMILES ON(C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCc2ccccc2N(CC(O)=O)C1=O)C=O Show InChI InChI=1S/C23H25N3O6/c27-15-25(32)13-18(12-16-6-2-1-3-7-16)22(30)24-19-11-10-17-8-4-5-9-20(17)26(23(19)31)14-21(28)29/h1-9,15,18-19,32H,10-14H2,(H,24,30)(H,28,29)/t18-,19+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Neutral endopeptidase |
Bioorg Med Chem Lett 10: 257-60 (2000)
BindingDB Entry DOI: 10.7270/Q2BK1BJ8 |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50085454
(CHEMBL90388 | N-formyl hydroxylamine containing di...)Show SMILES ON(C[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCc2ccccc2N(CC(O)=O)C1=O)C=O Show InChI InChI=1S/C23H25N3O6/c27-15-25(32)13-18(12-16-6-2-1-3-7-16)22(30)24-19-11-10-17-8-4-5-9-20(17)26(23(19)31)14-21(28)29/h1-9,15,18-19,32H,10-14H2,(H,24,30)(H,28,29)/t18-,19+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Angiotensin I converting enzyme |
Bioorg Med Chem Lett 10: 257-60 (2000)
BindingDB Entry DOI: 10.7270/Q2BK1BJ8 |
More data for this Ligand-Target Pair | |