Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 409.4 BDBM50285640

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50285640 ((S)-2-((R)-2-Benzyl-3-hydroxycarbamoyl-propionylam...) Show SMILES ONC(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O Show InChI InChI=1S/C22H23N3O5/c26-20(25-30)12-15(10-14-6-2-1-3-7-14)21(27)24-19(22(28)29)11-16-13-23-18-9-5-4-8-17(16)18/h1-9,13,15,19,23,30H,10-12H2,(H,24,27)(H,25,26)(H,28,29)/t15-,19+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Leukotriene A4 hydrolase				Bioorg Med Chem Lett 5: 2517-2522 (1995) Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M
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