Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 320.3 BDBM50285635

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50285635 ((S)-1-((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)-...) Show SMILES ONC(=O)C[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C16H20N2O5/c19-14(17-23)10-12(9-11-5-2-1-3-6-11)15(20)18-8-4-7-13(18)16(21)22/h1-3,5-6,12-13,23H,4,7-10H2,(H,17,19)(H,21,22)/t12-,13+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human Leukotriene A4 hydrolase				Bioorg Med Chem Lett 5: 2517-2522 (1995) Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50285635 ((S)-1-((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)-...) Show SMILES ONC(=O)C[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C16H20N2O5/c19-14(17-23)10-12(9-11-5-2-1-3-6-11)15(20)18-8-4-7-13(18)16(21)22/h1-3,5-6,12-13,23H,4,7-10H2,(H,17,19)(H,21,22)/t12-,13+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rabbit lung angiotensin-converting enzyme (ACE)				Bioorg Med Chem Lett 5: 2517-2522 (1995) Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M
					More data for this Ligand-Target Pair
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50285635 ((S)-1-((R)-2-Benzyl-3-hydroxycarbamoyl-propionyl)-...) Show SMILES ONC(=O)C[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C16H20N2O5/c19-14(17-23)10-12(9-11-5-2-1-3-6-11)15(20)18-8-4-7-13(18)16(21)22/h1-3,5-6,12-13,23H,4,7-10H2,(H,17,19)(H,21,22)/t12-,13+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against rabbit kidney neutral endopeptidase (NEP)				Bioorg Med Chem Lett 5: 2517-2522 (1995) Article DOI: 10.1016/0960-894X(95)00441-U BindingDB Entry DOI: 10.7270/Q2959J1M
					More data for this Ligand-Target Pair