Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-lactamase
(Pseudomonas aeruginosa) | BDBM98758
(US8487093, 122)Show SMILES OS(=O)(=O)ON1[C@H]2CN([C@@H](CC2)C(=O)NC[C@H]2CNCCCO2)C1=O |r| Show InChI InChI=1S/C13H22N4O7S/c18-12(15-7-10-6-14-4-1-5-23-10)11-3-2-9-8-16(11)13(19)17(9)24-25(20,21)22/h9-11,14H,1-8H2,(H,15,18)(H,20,21,22)/t9-,10-,11+/m1/s1 | PDB MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| KEGG PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp.
US Patent
| Assay Description Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay. |
US Patent US8487093 (2013)
BindingDB Entry DOI: 10.7270/Q2057DKK |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Klebsiella pneumoniae) | BDBM98758
(US8487093, 122)Show SMILES OS(=O)(=O)ON1[C@H]2CN([C@@H](CC2)C(=O)NC[C@H]2CNCCCO2)C1=O |r| Show InChI InChI=1S/C13H22N4O7S/c18-12(15-7-10-6-14-4-1-5-23-10)11-3-2-9-8-16(11)13(19)17(9)24-25(20,21)22/h9-11,14H,1-8H2,(H,15,18)(H,20,21,22)/t9-,10-,11+/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
| KEGG PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp.
US Patent
| Assay Description Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay. |
US Patent US8487093 (2013)
BindingDB Entry DOI: 10.7270/Q2057DKK |
More data for this Ligand-Target Pair | |