Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Polymerase acidic protein
() | BDBM474344
((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...)Show SMILES Oc1c2-c3ncc(Cl)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18ClN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2Z60S8G |
More data for this Ligand-Target Pair | |
Polymerase acidic protein
() | BDBM474344
((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...)Show SMILES Oc1c2-c3ncc(Cl)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18ClN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG
US Patent
| Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... |
US Patent US10858366 (2020)
BindingDB Entry DOI: 10.7270/Q2KH0RDJ |
More data for this Ligand-Target Pair | |