Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Polymerase acidic protein
() | BDBM474359
(3-((S)-(4-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...)Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(c3)C#N)n2ncc1=O |r| Show InChI InChI=1S/C23H16FN5O2/c24-17-6-4-15(5-7-17)20(16-3-1-2-14(10-16)11-25)18-13-28-9-8-26-23(28)21-22(31)19(30)12-27-29(18)21/h1-10,12,18,20,31H,13H2/t18-,20+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2Z60S8G |
More data for this Ligand-Target Pair | |
Polymerase acidic protein
() | BDBM474359
(3-((S)-(4-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...)Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(c3)C#N)n2ncc1=O |r| Show InChI InChI=1S/C23H16FN5O2/c24-17-6-4-15(5-7-17)20(16-3-1-2-14(10-16)11-25)18-13-28-9-8-26-23(28)21-22(31)19(30)12-27-29(18)21/h1-10,12,18,20,31H,13H2/t18-,20+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG
US Patent
| Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... |
US Patent US10858366 (2020)
BindingDB Entry DOI: 10.7270/Q2KH0RDJ |
More data for this Ligand-Target Pair | |