Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 369.4 BDBM474343

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein ()	BDBM474343 ((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...) Show SMILES Oc1c2-c3nccn3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H19N3O2/c27-19-11-13-26-18(15-25-14-12-24-23(25)21(26)22(19)28)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,18,20,28H,15H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474343 ((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...) Show SMILES Oc1c2-c3nccn3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H19N3O2/c27-19-11-13-26-18(15-25-14-12-24-23(25)21(26)22(19)28)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,18,20,28H,15H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair