Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Polymerase acidic protein
() | BDBM474342
(6-benzhydryl-11-hydroxy-5,6-dihydro-10H- [1,2,4]tr...)Show SMILES Oc1c2-c3ncnn3CC(C(c3ccccc3)c3ccccc3)n2ncc1=O Show InChI InChI=1S/C21H17N5O2/c27-17-11-23-26-16(12-25-21(22-13-24-25)19(26)20(17)28)18(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-11,13,16,18,28H,12H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2Z60S8G |
More data for this Ligand-Target Pair | |
Polymerase acidic protein
() | BDBM474342
(6-benzhydryl-11-hydroxy-5,6-dihydro-10H- [1,2,4]tr...)Show SMILES Oc1c2-c3ncnn3CC(C(c3ccccc3)c3ccccc3)n2ncc1=O Show InChI InChI=1S/C21H17N5O2/c27-17-11-23-26-16(12-25-21(22-13-24-25)19(26)20(17)28)18(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-11,13,16,18,28H,12H2 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG
US Patent
| Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/... |
US Patent US10858366 (2020)
BindingDB Entry DOI: 10.7270/Q2KH0RDJ |
More data for this Ligand-Target Pair | |