Found 5 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM61181
(2-(2,4-dichlorophenyl)-4-(1,3-dioxo-1,3-dihydro-2H...)Show SMILES Oc1c2C(N=C(C3C(=O)c4ccccc4C3=O)c2c(O)n1-c1ccc(Cl)cc1Cl)c1ccccn1 |t:4,(14.45,.48,;12.91,.49,;12.01,1.73,;12.01,3.27,;10.55,3.74,;9.64,2.5,;8.1,2.5,;7.2,1.26,;7.68,-.21,;5.75,1.73,;4.41,.96,;3.08,1.73,;3.08,3.27,;4.41,4.04,;5.75,3.27,;7.2,3.74,;7.68,5.2,;10.55,1.25,;10.55,-.28,;9.31,-1.19,;12.01,-.75,;12.49,-2.22,;13.99,-2.54,;14.47,-4,;13.44,-5.14,;13.91,-6.61,;11.93,-4.82,;11.45,-3.36,;9.95,-3.04,;13.26,4.17,;14.67,3.55,;15.91,4.45,;15.75,5.98,;14.34,6.61,;13.1,5.7,)| Show InChI InChI=1S/C26H15Cl2N3O4/c27-12-8-9-17(15(28)11-12)31-25(34)18-19(26(31)35)22(30-21(18)16-7-3-4-10-29-16)20-23(32)13-5-1-2-6-14(13)24(20)33/h1-11,20-21,34-35H | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| PCBioAssay
| n/a | n/a | 5.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this
Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM61181
(2-(2,4-dichlorophenyl)-4-(1,3-dioxo-1,3-dihydro-2H...)Show SMILES Oc1c2C(N=C(C3C(=O)c4ccccc4C3=O)c2c(O)n1-c1ccc(Cl)cc1Cl)c1ccccn1 |t:4,(14.45,.48,;12.91,.49,;12.01,1.73,;12.01,3.27,;10.55,3.74,;9.64,2.5,;8.1,2.5,;7.2,1.26,;7.68,-.21,;5.75,1.73,;4.41,.96,;3.08,1.73,;3.08,3.27,;4.41,4.04,;5.75,3.27,;7.2,3.74,;7.68,5.2,;10.55,1.25,;10.55,-.28,;9.31,-1.19,;12.01,-.75,;12.49,-2.22,;13.99,-2.54,;14.47,-4,;13.44,-5.14,;13.91,-6.61,;11.93,-4.82,;11.45,-3.36,;9.95,-3.04,;13.26,4.17,;14.67,3.55,;15.91,4.45,;15.75,5.98,;14.34,6.61,;13.1,5.7,)| Show InChI InChI=1S/C26H15Cl2N3O4/c27-12-8-9-17(15(28)11-12)31-25(34)18-19(26(31)35)22(30-21(18)16-7-3-4-10-29-16)20-23(32)13-5-1-2-6-14(13)24(20)33/h1-11,20-21,34-35H | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this
Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM61181
(2-(2,4-dichlorophenyl)-4-(1,3-dioxo-1,3-dihydro-2H...)Show SMILES Oc1c2C(N=C(C3C(=O)c4ccccc4C3=O)c2c(O)n1-c1ccc(Cl)cc1Cl)c1ccccn1 |t:4,(14.45,.48,;12.91,.49,;12.01,1.73,;12.01,3.27,;10.55,3.74,;9.64,2.5,;8.1,2.5,;7.2,1.26,;7.68,-.21,;5.75,1.73,;4.41,.96,;3.08,1.73,;3.08,3.27,;4.41,4.04,;5.75,3.27,;7.2,3.74,;7.68,5.2,;10.55,1.25,;10.55,-.28,;9.31,-1.19,;12.01,-.75,;12.49,-2.22,;13.99,-2.54,;14.47,-4,;13.44,-5.14,;13.91,-6.61,;11.93,-4.82,;11.45,-3.36,;9.95,-3.04,;13.26,4.17,;14.67,3.55,;15.91,4.45,;15.75,5.98,;14.34,6.61,;13.1,5.7,)| Show InChI InChI=1S/C26H15Cl2N3O4/c27-12-8-9-17(15(28)11-12)31-25(34)18-19(26(31)35)22(30-21(18)16-7-3-4-10-29-16)20-23(32)13-5-1-2-6-14(13)24(20)33/h1-11,20-21,34-35H | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this
Ligand-Target Pair | |
SUMO-activating enzyme subunit 1
(Homo sapiens (Human)) | BDBM61181
(2-(2,4-dichlorophenyl)-4-(1,3-dioxo-1,3-dihydro-2H...)Show SMILES Oc1c2C(N=C(C3C(=O)c4ccccc4C3=O)c2c(O)n1-c1ccc(Cl)cc1Cl)c1ccccn1 |t:4,(14.45,.48,;12.91,.49,;12.01,1.73,;12.01,3.27,;10.55,3.74,;9.64,2.5,;8.1,2.5,;7.2,1.26,;7.68,-.21,;5.75,1.73,;4.41,.96,;3.08,1.73,;3.08,3.27,;4.41,4.04,;5.75,3.27,;7.2,3.74,;7.68,5.2,;10.55,1.25,;10.55,-.28,;9.31,-1.19,;12.01,-.75,;12.49,-2.22,;13.99,-2.54,;14.47,-4,;13.44,-5.14,;13.91,-6.61,;11.93,-4.82,;11.45,-3.36,;9.95,-3.04,;13.26,4.17,;14.67,3.55,;15.91,4.45,;15.75,5.98,;14.34,6.61,;13.1,5.7,)| Show InChI InChI=1S/C26H15Cl2N3O4/c27-12-8-9-17(15(28)11-12)31-25(34)18-19(26(31)35)22(30-21(18)16-7-3-4-10-29-16)20-23(32)13-5-1-2-6-14(13)24(20)33/h1-11,20-21,34-35H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PCBioAssay
| n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2BP0175 |
More data for this
Ligand-Target Pair | |
SUMO-conjugating enzyme UBC9
(Homo sapiens (Human)) | BDBM61181
(2-(2,4-dichlorophenyl)-4-(1,3-dioxo-1,3-dihydro-2H...)Show SMILES Oc1c2C(N=C(C3C(=O)c4ccccc4C3=O)c2c(O)n1-c1ccc(Cl)cc1Cl)c1ccccn1 |t:4,(14.45,.48,;12.91,.49,;12.01,1.73,;12.01,3.27,;10.55,3.74,;9.64,2.5,;8.1,2.5,;7.2,1.26,;7.68,-.21,;5.75,1.73,;4.41,.96,;3.08,1.73,;3.08,3.27,;4.41,4.04,;5.75,3.27,;7.2,3.74,;7.68,5.2,;10.55,1.25,;10.55,-.28,;9.31,-1.19,;12.01,-.75,;12.49,-2.22,;13.99,-2.54,;14.47,-4,;13.44,-5.14,;13.91,-6.61,;11.93,-4.82,;11.45,-3.36,;9.95,-3.04,;13.26,4.17,;14.67,3.55,;15.91,4.45,;15.75,5.98,;14.34,6.61,;13.1,5.7,)| Show InChI InChI=1S/C26H15Cl2N3O4/c27-12-8-9-17(15(28)11-12)31-25(34)18-19(26(31)35)22(30-21(18)16-7-3-4-10-29-16)20-23(32)13-5-1-2-6-14(13)24(20)33/h1-11,20-21,34-35H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| PCBioAssay
| n/a | n/a | 3.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2V986G8 |
More data for this
Ligand-Target Pair | |