Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 397.2 BDBM85663

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM85663 (Tetrahydroisoquinoline hydantoin derivative, 3c) Show SMILES Oc1c2Cc3ccccc3-n2c(=O)n1S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H10Cl2N2O4S/c17-11-6-5-10(8-12(11)18)25(23,24)20-15(21)14-7-9-3-1-2-4-13(9)19(14)16(20)22/h1-6,8,21H,7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.74E+5	n/a	n/a	n/a	n/a	n/a	n/a
Université de Tours					Assay Description Enzyme inhibitory activity using recombinant human chymase.				J Enzyme Inhib Med Chem 19: 137-43 (2004) Article DOI: 10.1080/14756360310001650200 BindingDB Entry DOI: 10.7270/Q2VM49TK
					More data for this Ligand-Target Pair