Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM210828
(US10463663, Example 68 | US11129828, Example 68 | ...)Show InChI InChI=1S/C13H10F4N2O2/c14-10-5-7(2-4-9(10)13(15,16)17)1-3-8-6-11(20)12(21)19-18-8/h2,4-6H,1,3H2,(H,18,20)(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le... |
US Patent US9290456 (2016)
BindingDB Entry DOI: 10.7270/Q2RF5SW0 |
More data for this Ligand-Target Pair | |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM210828
(US10463663, Example 68 | US11129828, Example 68 | ...)Show InChI InChI=1S/C13H10F4N2O2/c14-10-5-7(2-4-9(10)13(15,16)17)1-3-8-6-11(20)12(21)19-18-8/h2,4-6H,1,3H2,(H,18,20)(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q27W6GCR |
More data for this Ligand-Target Pair | |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM210828
(US10463663, Example 68 | US11129828, Example 68 | ...)Show InChI InChI=1S/C13H10F4N2O2/c14-10-5-7(2-4-9(10)13(15,16)17)1-3-8-6-11(20)12(21)19-18-8/h2,4-6H,1,3H2,(H,18,20)(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description The functional activity of compounds inhibiting the DAAO enzyme was determined by utilizing the co-product of the catalysis of D-Serine, H2O2 which c... |
US Patent US10463663 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BXG |
More data for this Ligand-Target Pair | |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM210828
(US10463663, Example 68 | US11129828, Example 68 | ...)Show InChI InChI=1S/C13H10F4N2O2/c14-10-5-7(2-4-9(10)13(15,16)17)1-3-8-6-11(20)12(21)19-18-8/h2,4-6H,1,3H2,(H,18,20)(H,19,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description Human DAAO enzyme was supplied by the Takeda Pharmaceutical Company (Osaka) and each batch was tested and used at concentrations giving comparable le... |
Bioorg Med Chem Lett 18: 4282-6 (2008)
BindingDB Entry DOI: 10.7270/Q2F76FWC |
More data for this Ligand-Target Pair | |