Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 286.2 BDBM50176527

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176527 (6,8-dihydroxy-3-(3',5'-dihydroxyphenyl)coumarin | ...) Show SMILES Oc1cc(O)cc(c1)-c1cc2cc(O)cc(O)c2oc1=O Show InChI InChI=1S/C15H10O6/c16-9-1-7(2-10(17)5-9)12-4-8-3-11(18)6-13(19)14(8)21-15(12)20/h1-6,16-19H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50176527 (6,8-dihydroxy-3-(3',5'-dihydroxyphenyl)coumarin | ...) Show SMILES Oc1cc(O)cc(c1)-c1cc2cc(O)cc(O)c2oc1=O Show InChI InChI=1S/C15H10O6/c16-9-1-7(2-10(17)5-9)12-4-8-3-11(18)6-13(19)14(8)21-15(12)20/h1-6,16-19H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.85E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of thrombin-induced platelet aggregation in human				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
					More data for this Ligand-Target Pair